Which Cancers Are Associated with CTNNB1 Mutations?
CTNNB1 mutations have been implicated in several types of cancers. In hepatocellular carcinoma, these mutations are among the most frequently observed. Similarly, CTNNB1 mutations are found in a significant percentage of cases of endometrial cancer and desmoid tumors. Furthermore, these mutations are also linked to melanoma and medulloblastomas, underscoring the gene's widespread influence in oncogenesis.
