Which Genes are Commonly Hypermethylated in Cancer?
Several genes are commonly hypermethylated in different types of cancer. For example, the p16INK4a gene, which is involved in cell cycle regulation, is frequently hypermethylated in cancers such as lung, breast, and colon cancer. Another example is the BRCA1 gene, known for its role in DNA repair, which is often hypermethylated in breast and ovarian cancers.