Why Are Binding Sites Important for Drug Development?
Targeting specific binding sites on cancer cells is a key strategy in drug development. By designing molecules that specifically bind to these sites, researchers can develop therapies that are more effective and have fewer side effects. For example, tyrosine kinase inhibitors target the ATP-binding site of tyrosine kinase enzymes, which are often overactive in cancer cells. This selective inhibition can halt the growth of cancerous cells without affecting normal cells.