Micelles offer several advantages in cancer therapy: 1. Enhanced Permeability and Retention (EPR) Effect: Tumors often have leaky blood vessels and poor lymphatic drainage, allowing micelles to accumulate more in tumor tissues compared to normal tissues. 2. Reduced Toxicity: By targeting drug delivery specifically to tumor cells, micelles help in minimizing the systemic toxicity often associated with conventional chemotherapy. 3. Improved Solubility: Micelles can encapsulate hydrophobic drugs, enhancing their solubility in the bloodstream and improving bioavailability. 4. Controlled Release: Micelles can be engineered to release their drug payload in response to specific stimuli like pH changes, temperature, or enzymatic activity, providing controlled and sustained drug release.
