Glutamine plays several essential roles in the metabolism of cancer cells. It is a key substrate for the production of energy, serving as a carbon and nitrogen source for the synthesis of nucleotides, amino acids, and other biomolecules. Additionally, glutamine is involved in maintaining the redox balance within cells by contributing to the production of glutathione, an important antioxidant. This multifaceted role makes glutamine indispensable for the growth and proliferation of many cancer cells.