gene amplification

Why is Gene Amplification Important in Cancer?

Gene amplification has several implications in cancer:
Promotes Tumor Growth: Amplified oncogenes can enhance cell proliferation and survival.
Drug Resistance: Genes involved in drug metabolism or efflux, when amplified, can lead to chemotherapy resistance.
Diagnostic and Prognostic Marker: Gene amplification can serve as a biomarker for specific cancers, aiding in diagnosis and prognosis.

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