Targeting CAIX in cancer therapy is promising for several reasons:
Tumor Microenvironment: CAIX helps cancer cells survive in the acidic and hypoxic conditions of the tumor microenvironment by regulating pH levels. Metastasis: CAIX is involved in processes that enable cancer cells to metastasize or spread to other parts of the body. Drug Resistance: CAIX expression can contribute to resistance against conventional therapies, making it a valuable target for combination treatments.
