Mutations In The Brca1 And Brca2 Genes - Cancer Science

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Germline mutations of breast cancer susceptibility genes through expanded genetic analysis in unselected Colombian patients.

Issue Release: 2024

Molecular insights into TP53 mutation (p. Arg267Trp) and its connection to Choroid Plexus Carcinomas and Li-Fraumeni Syndrome.

Issue Release: 2024

Spectrum and characteristics of germline PALB2 pathogenic variants in 1556 early-onset breast cancer patients in China.

Issue Release: 2024

Genetic intratumour heterogeneity and clonal evolution in extramammary Paget\'s disease.

Issue Release: 2024

Outcomes of a universal germline screening program in a community urology practice.

Issue Release: 2024

Olaparib monotherapy or in combination with abiraterone for treating mutated metastatic castration-resistant prostate cancer: alone or stronger together?

Issue Release: 2024

Molecular analysis of non-small cell lung cancer using a dual-targeted DNA and RNA comprehensive genomic profiling panel.

Issue Release: 2024

Real-world data on the prevalence of BRCA1/2 and HRR gene mutations in patients with primary and metastatic castration resistant prostate cancer.

Issue Release: 2024

BRCA-mutated breast cancer: the unmet need, challenges and therapeutic benefits of genetic testing.

Issue Release: 2024

Clinical Impact of Constitutional Genomic Testing on Current Breast Cancer Care.

Issue Release: 2024

Assessing olaparib efficacy in U.S. Veterans with metastatic prostate cancer utilizing a time-indifferent g-rate method ideal for real-world analyses.

Issue Release: 2024

Genomic landscape of liquid biopsy mutations in TP53 and DNA damage genes in cancer patients.

Issue Release: 2024

Prevalence and spectrum of germline BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health.

Issue Release: 2024

A Phase II Study of Rucaparib Monotherapy in Nonmetastatic, Hormone-Sensitive Prostate Cancer Demonstrating \"BRCAness\" Genotype (ROAR).

Issue Release: 2024

Germline mutational variants of Turkish ovarian cancer patients suspected of Hereditary Breast and Ovarian Cancer (HBOC) by next-generation sequencing.

Issue Release: 2024

Characterization of immortalized ovarian epithelial cells with BRCA1/2 mutation.

Issue Release: 2024

PALB2-mutated human mammary cells display a broad spectrum of morphological and functional abnormalities induced by increased TGFβ signaling.

Issue Release: 2024

Biomarker Testing Journey Among Patients with Advanced Solid Tumors and Treatment Patterns by Homologous Recombination Repair Status: A Clinico-Genomic Database Study.

Issue Release: 2024

EXO1 protects BRCA1-deficient cells against toxic DNA lesions.

Issue Release: 2024

Deciphering DNA repair gene mutational landscape in uterine corpus endometrial carcinoma patients using next generation sequencing.

Issue Release: 2024

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