Are There Diagnostic or Prognostic Applications for ABC Transporters in Cancer?
The expression levels of certain ABC transporters can be used as biomarkers for predicting treatment response and disease prognosis. For instance, high levels of ABCB1 or ABCG2 expression in tumors are often associated with poor prognosis and reduced survival rates. Biomarker assays that measure ABC transporter expression could help tailor treatment strategies for individual patients.