Despite its wide utility, FDG-PET scans have some limitations:
1. False Positives: Inflamed or infected tissues can also show increased FDG uptake, leading to false-positive results. 2. False Negatives: Some types of cancer, such as low-grade tumors, may not have high glucose metabolism and can be missed. 3. Cost and Accessibility: FDG-PET scans are expensive and may not be readily available in all healthcare settings. 4. Radiation Exposure: Although the radiation dose is relatively low, repeated scans may pose a risk over time.