Can DNA Polymerases Be Targeted for Cancer Therapy?
Targeting DNA polymerases for cancer therapy is an area of active research. Given their critical role in DNA replication and repair, inhibiting these enzymes can potentially halt the proliferation of cancer cells. For instance, polymerase inhibitors have been explored as therapeutic agents. However, the challenge lies in selectively targeting cancer cells without affecting normal cells, as DNA polymerases are essential for the survival of all dividing cells.
