Can Inflammatory Cells Be Targeted for Cancer Therapy?
Yes, targeting inflammatory cells is a promising strategy for cancer therapy. Various approaches are being explored to modulate the activity of inflammatory cells to enhance anti-tumor immunity. For example, therapies targeting TAMs aim to re-polarize them from a pro-tumor M2 phenotype to an anti-tumor M1 phenotype. Similarly, strategies to inhibit neutrophil recruitment and function are being investigated to reduce their pro-tumor activities.
