Can Intermediate Filaments Serve as Therapeutic Targets?
Given their involvement in cancer progression, intermediate filaments present potential therapeutic targets. Strategies to inhibit vimentin and disrupt IF dynamics are being explored to prevent metastasis and enhance the efficacy of existing treatments. Additionally, targeting the signaling pathways that regulate IF assembly and disassembly could provide novel approaches to cancer therapy. However, the challenge lies in achieving specificity, as IFs are also essential for normal cellular functions.