Overcoming intrinsic resistance is a significant challenge but not impossible. Strategies include:
- Combination Therapies: Using multiple drugs that target different pathways can help to overcome resistance. - New Drug Development: Designing drugs that can bypass or inhibit the mechanisms of intrinsic resistance. - Targeted Therapies: Drugs that specifically target the genetic mutations responsible for resistance can be more effective. - Immunotherapy: Harnessing the body's immune system to target cancer cells offers a promising avenue for overcoming intrinsic resistance.