Which Cancers Commonly Exhibit Intrinsic Resistance?
Intrinsic resistance can be found in various types of cancers, including but not limited to:
- Glioblastoma: This aggressive brain tumor often shows intrinsic resistance to standard chemotherapies like temozolomide. - Pancreatic Cancer: Known for its poor prognosis, pancreatic cancer frequently exhibits intrinsic resistance to multiple drugs, including gemcitabine. - Melanoma: Some melanomas have intrinsic resistance to BRAF inhibitors due to mutations in the MAPK pathway. - Non-Small Cell Lung Cancer (NSCLC): Certain subtypes of NSCLC exhibit intrinsic resistance to targeted therapies like EGFR inhibitors.
