Targeting keratins for cancer therapy represents a promising yet challenging area of research. Since keratins are involved in numerous cellular processes, directly targeting them could potentially disrupt normal cell function leading to adverse effects. However, understanding the specific alterations in keratin expression associated with cancer can provide insights into potential therapeutic targets. Researchers are exploring ways to modulate keratin function or expression to inhibit cancer cell growth and metastasis, although this is still largely in the experimental stages.