Keratins are a group of fibrous structural proteins that are key components of the cytoskeleton in epithelial cells, providing structural support and playing a critical role in cellular functions. They are divided into two main types: type I (acidic keratins) and type II (basic or neutral keratins), which form heterodimers that assemble into intermediate filaments. These proteins are essential for maintaining the integrity and resilience of epithelial tissues.