Can Non-Coding RNAs Influence Cancer Transcription?
Yes, non-coding RNAs, such as microRNAs and long non-coding RNAs (lncRNAs), play significant roles in the regulation of transcription. These molecules can modulate the expression of oncogenes and tumor suppressor genes by interacting with transcription factors or directly with the DNA. Dysregulation of non-coding RNAs is a common feature in cancer and can contribute to tumor initiation and progression.