Targeting progenitor cells and their pathways offers a promising avenue for cancer treatment. Therapies that specifically target the unique properties of progenitor cells or CSCs may improve treatment outcomes. For example, differentiation therapy aims to induce cancer cells to differentiate into a more mature, non-proliferative state. Additionally, targeting the signaling pathways that regulate progenitor cell proliferation and survival, such as the Notch, Wnt, and Hedgehog pathways, could potentially eliminate CSCs and reduce the likelihood of cancer recurrence.
