What Are the Challenges in Targeting Progenitor Cells?
One of the primary challenges in targeting progenitor cells is their similarity to normal stem cells, which are essential for tissue homeostasis and repair. Therapies must be carefully designed to specifically target cancerous progenitor cells without harming normal stem cells. Additionally, the plasticity of cancer cells, their ability to evolve and adapt, presents another significant challenge. This adaptability can lead to resistance against therapies that target specific cell types or pathways.
