Can We Target the Microenvironment for Cancer Therapy?
Yes, targeting the microenvironment offers a promising approach for cancer therapy. Strategies include:
Anti-angiogenic Therapies: These aim to inhibit the formation of new blood vessels, starving the tumor of nutrients and oxygen. Immunotherapy: Enhancing the immune system's ability to recognize and attack cancer cells by modulating the microenvironment. Disrupting ECM Interactions: Targeting the ECM components to prevent cancer cells from receiving the necessary support for growth and invasion. Modulating Signaling Pathways: Using drugs to interfere with the signaling molecules that promote cancer cell survival and proliferation.
