chromosomal translocations

How are Chromosomal Translocations Detected?

Detecting chromosomal translocations typically involves techniques such as fluorescence in situ hybridization (FISH), which uses fluorescent probes to identify specific DNA sequences on chromosomes. Another common method is polymerase chain reaction (PCR), which can amplify and detect fusion genes resulting from translocations. Additionally, next-generation sequencing (NGS) provides a comprehensive approach to identify and characterize translocations at a genomic level.

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