oncogenic fusion proteins

How Are Fusion Proteins Detected?

Detection of fusion proteins can be achieved through various molecular techniques. Fluorescence in situ hybridization (FISH) is commonly used to identify specific chromosomal translocations. Additionally, reverse transcription-polymerase chain reaction (RT-PCR) can detect and amplify fusion transcripts, while next-generation sequencing offers a comprehensive approach to identify known and novel fusions.

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