immunocytochemistry

What Are Some Key Markers Detected by ICC in Cancer?

- Estrogen Receptor (ER): Commonly detected in breast cancer to determine hormone receptor status.
- HER2/neu: A protein overexpressed in certain types of breast cancer, important for targeted therapy decisions.
- p53: A tumor suppressor protein that is often mutated in various cancers.
- Ki-67: A marker of cell proliferation, used to assess the growth rate of tumors.
- Cytokeratins: Intermediate filament proteins used to identify epithelial cells and carcinomas.

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