What are the Treatment Options for BRAF-Mutant Cancers?
The treatment of BRAF-mutant cancers has been revolutionized by the development of targeted therapies. BRAF inhibitors like vemurafenib and dabrafenib have shown significant efficacy in treating BRAF V600E mutated melanoma. Additionally, combining BRAF inhibitors with MEK inhibitors such as trametinib can further improve outcomes by blocking the MAPK pathway at multiple points.