What Types of Genetic Mutations Are Common in Cancer?
Several types of genetic mutations are commonly associated with cancer, including:
1. Point Mutations: A single nucleotide change can lead to a dysfunctional protein. 2. Insertions and Deletions (Indels): These mutations involve the addition or loss of small DNA segments, which can disrupt gene function. 3. Copy Number Variations (CNVs): Changes in the number of copies of a gene can affect gene expression levels. 4. Chromosomal Rearrangements: These include translocations, inversions, and duplications, which can lead to oncogene activation or tumor suppressor gene inactivation.