Selection of Model: Choose an appropriate animal model based on the type of cancer and research objectives. Induction of Cancer: Introduce cancer cells or carcinogens to develop tumors within the model organism. Treatment Administration: Administer the test compounds, which could be chemotherapeutic agents, immunotherapies, or other experimental treatments. Monitoring: Regularly monitor the animals for signs of tumor growth, metastasis, and overall health. Data Collection: Collect and analyze data on the efficacy and safety of the treatment.