microtubule function

How Are Microtubules Targeted in Cancer Therapy?

Several classes of anticancer drugs target microtubules to disrupt their dynamics and inhibit cancer cell division. These include:
Taxanes: Stabilize microtubules and prevent their depolymerization, leading to cell cycle arrest.
Vinca Alkaloids: Bind to tubulin and inhibit microtubule polymerization, causing mitotic arrest.
Epothilones: Similar to taxanes, they stabilize microtubules but differ in their binding sites and molecular structure.

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