Several classes of anticancer drugs target microtubules to disrupt their dynamics and inhibit cancer cell division. These include:
Taxanes: Stabilize microtubules and prevent their depolymerization, leading to cell cycle arrest. Vinca Alkaloids: Bind to tubulin and inhibit microtubule polymerization, causing mitotic arrest. Epothilones: Similar to taxanes, they stabilize microtubules but differ in their binding sites and molecular structure.