How are molecular pathways targeted in cancer therapy?
Understanding the molecular pathways involved in cancer has led to the development of targeted therapies designed to inhibit specific components of these pathways. For example, tyrosine kinase inhibitors target specific kinases involved in the RAS/RAF/MEK/ERK pathway, while mTOR inhibitors are used to block the PI3K/AKT/mTOR pathway. Additionally, drugs targeting the p53 pathway aim to restore its tumor suppressor function.
