The creation of personalized tumor models involves several key steps:
Tissue Sample Collection: Tumor samples are obtained from a patient's biopsy or surgical resection. Genetic Sequencing: The tumor's DNA is sequenced to identify specific mutations and molecular characteristics. Model Development: Using this genetic information, scientists develop a model, which may include patient-derived xenografts (PDX), organoids, or 3D bioprinting. Drug Testing: Potential treatments are tested on these models to assess efficacy and safety.