protein protein interaction networks

How Are PPI Networks Constructed?

PPI networks are constructed using various experimental and computational methods. Experimental methods include techniques such as yeast two-hybrid screening, co-immunoprecipitation (Co-IP), and affinity purification mass spectrometry (AP-MS). Computational approaches often involve integrating data from multiple sources, including genomic, proteomic, and bioinformatics databases, to predict interactions and build comprehensive networks.

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