How are Serotonin Antagonists Used in Cancer Treatment?
In the context of cancer, serotonin antagonists are primarily used to manage chemotherapy-induced nausea and vomiting (CINV). These symptoms are common side effects of cancer treatments and can significantly impair the quality of life for patients. By blocking serotonin receptors, particularly the 5-HT3 receptors located in the brain and gastrointestinal tract, these drugs help reduce nausea and vomiting.