The development of specific inhibitors involves a multi-step process:
1. Target Identification: Researchers first identify and validate a target molecule that plays a crucial role in cancer cell survival and proliferation. 2. Drug Design: Using techniques like high-throughput screening and computer-aided design, compounds are developed that can specifically bind to the target. 3. Preclinical Testing: Potential inhibitors are tested in cell lines and animal models to evaluate their efficacy and safety. 4. Clinical Trials: Compounds that pass preclinical testing move on to clinical trials, where their safety and effectiveness are tested in humans.
