xenograft

How Are Xenografts Created?


The creation of a xenograft typically involves several steps:
Cell or Tissue Harvesting: Human cancer cells or tissues are obtained from patient biopsies or established cell lines.
Preparation: The harvested cells are processed and sometimes genetically modified to express markers that facilitate tracking and imaging.
Implantation: The processed cells are implanted into immunocompromised mice, which lack an adequate immune response to reject the foreign cells.
Monitoring: Tumor growth and progression are monitored using various techniques such as imaging and biomarker analysis.

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