Funcotator has several applications in cancer research:
Identification of Driver Mutations: By annotating variants, researchers can identify potential driver mutations that contribute to cancer progression. Development of Targeted Therapies: Understanding the functional impact of mutations can guide the development of targeted therapies that specifically address the underlying genetic causes of a patient's cancer. Personalized Treatment: Annotation helps in tailoring personalized treatment plans based on the unique genetic profile of a patient's tumor. Biomarker Discovery: Annotated variants can serve as biomarkers for cancer diagnosis, prognosis, and monitoring treatment response.