How Can Gene Expression Be Targeted Therapeutically?
Targeting gene expression therapeutically involves strategies to either suppress or enhance the expression of specific genes. Antisense oligonucleotides and siRNA can be used to block the expression of oncogenes. Conversely, gene therapy can be employed to restore the function of tumor suppressor genes. Moreover, epigenetic therapies aim to reverse abnormal gene expression patterns by modifying DNA methylation and histone acetylation.