Several strategies can be employed to improve light penetration for cancer treatments:
1. Use of Optical Fibers: Optical fibers can be inserted into the body to deliver light directly to the tumor site. This minimizes the scattering and absorption by surrounding tissues. 2. Advanced Imaging Techniques: Combining light-based therapy with imaging techniques like MRI or ultrasound can help guide the precise delivery of light to the targeted area. 3. Nanoparticles: Employing nanoparticles that can absorb and re-emit light can enhance penetration. These can be tailored to specific wavelengths that penetrate deeper into tissues. 4. Tissue-Optical Clearing Agents: These agents reduce the scattering of light within the tissue, allowing deeper penetration. They work by temporarily altering the refractive index of tissues.