Several strategies can be employed to improve oxygenation in tumors:
Hyperbaric Oxygen Therapy (HBOT): This involves breathing pure oxygen in a pressurized room, which can increase the oxygen concentration in the blood and, subsequently, in the tumor tissue. Normobaric Oxygen Therapy: This method uses high-flow oxygen at normal atmospheric pressure to increase tissue oxygenation. Pharmacological Agents: Certain drugs, such as nicotinamide and erythropoietin, can enhance oxygen delivery or reduce oxygen consumption by the tumor. Anti-angiogenic Therapy: By normalizing the abnormal blood vessels within tumors, anti-angiogenic agents can improve blood flow and oxygen delivery.
