Increasing Sample Diversity: Ensuring that the study population includes a diverse range of participants can help improve generalizability. Multi-Center Trials: Conducting research across multiple centers and regions can help account for geographic and demographic variations. Real-World Evidence: Incorporating real-world data along with traditional clinical trials can provide a more comprehensive understanding of how treatments work across different populations. Collaborative Research: Collaborative efforts between different institutions and countries can enhance the scope and applicability of cancer research findings.