How Does Extracellular Fluid Influence Cancer Progression?
In cancer, the ECF environment is often modified to support tumor growth. Tumors can alter the ECF by secreting growth factors and enzymes that degrade the extracellular matrix (ECM), facilitating invasion and metastasis. Changes in the ECF can also affect the acidity, oxygen levels, and nutrient availability, creating a microenvironment that favors cancer cell survival and proliferation.
