How Can We Optimize the Use of Active Metabolites in Cancer Treatment?
Optimizing the use of active metabolites in cancer treatment involves several strategies:
Therapeutic Drug Monitoring (TDM): Regular monitoring of drug and metabolite levels can help in adjusting doses to achieve optimal therapeutic effects while minimizing toxicity. Pharmacogenomic Testing: Identifying genetic variations that affect drug metabolism can guide personalized treatment plans. Combination Therapies: Using drugs that can modulate the activity of enzymes involved in metabolite formation can enhance the efficacy of cancer treatments.