How do BRCA1 and BRCA2 mutations contribute to cancer?
Mutations in BRCA1 and BRCA2 can lead to the loss of function in the proteins they encode, impairing the cell's ability to repair DNA damage. This can result in genetic mutations accumulating over time, which may lead to uncontrolled cell growth and cancer. Individuals who inherit harmful mutations in these genes have a significantly higher risk of developing breast, ovarian, and other cancers.
