How do Cell Surface Receptors Contribute to Cancer?
In the context of cancer, cell surface receptors play a pivotal role in disease progression and metastasis. Abnormal activation or overexpression of these receptors can lead to uncontrolled cell proliferation, evasion of apoptosis, and increased invasiveness. For instance, the overexpression of the [Epidermal Growth Factor Receptor (EGFR)]() and the [Human Epidermal Growth Factor Receptor 2 (HER2)]() has been linked to various cancers, including breast, lung, and colorectal cancers.