How Do Checkpoint Inhibitors Enhance Immune Surveillance?
Checkpoint inhibitors are drugs that block proteins used by cancer cells to turn off immune responses, effectively "releasing the brakes" on the immune system. For example, PD-1/PD-L1 inhibitors prevent the interaction between the PD-1 receptor on T cells and its ligand PD-L1 on cancer cells, allowing T cells to recognize and kill cancer cells more effectively.