How Do Chemotherapy and Radiation Cause Nausea and Vomiting?
Chemotherapy-induced nausea and vomiting (CINV) occur because chemotherapy drugs can affect the central nervous system and the gastrointestinal tract. These drugs release neurotransmitters like serotonin, which activate the vomiting center in the brain. Radiation therapy, particularly when administered to the abdomen or pelvis, can irritate the lining of the stomach and intestines, leading to nausea. The extent of these side effects can depend on the type of chemotherapy or radiation used, the dosage, and the treatment schedule.
