Cytokine inhibitors function by blocking the activity of specific cytokines or their receptors. This can be achieved through various mechanisms: 1. Monoclonal Antibodies: These are engineered antibodies that specifically bind to cytokines or their receptors, neutralizing their activity. For example, [Tocilizumab](href="") targets the IL-6 receptor. 2. Small Molecule Inhibitors: These are low molecular weight compounds that interfere with cytokine signaling pathways. For example, [JAK inhibitors](href="") block the Janus kinase enzymes involved in cytokine signaling. 3. Soluble Receptors: These are engineered proteins that mimic the natural receptors of cytokines, binding them and preventing their interaction with cell surface receptors.