How Do Microfilaments Contribute to Cancer Cell Invasion and Metastasis?
Cancer cell invasion and metastasis are heavily dependent on the ability of cancer cells to remodel their cytoskeleton, particularly the actin network. Through the reorganization of microfilaments, cancer cells can penetrate the basement membrane and invade adjacent tissues. Additionally, microfilaments facilitate the transition of cancer cells through the bloodstream or lymphatic system to distant organs, a process known as metastasis. The remodeling of microfilaments allows cancer cells to maintain their structural integrity while navigating through complex environments.
