How Do Researchers Use Functional Genomics to Study Cancer?
Researchers employ several techniques in functional genomics to study cancer:
Gene Expression Profiling: This involves measuring the activity of thousands of genes at once to create a global picture of cellular function. Techniques such as RNA-Seq are commonly used. CRISPR-Cas9: This gene-editing technology allows scientists to knock out or modify specific genes to study their function and role in cancer. Proteomics: This is the large-scale study of proteins, including their expression, modification, and interaction. It provides insights into the functional consequences of genetic mutations. Chromatin Immunoprecipitation (ChIP): This technique is used to study protein-DNA interactions and helps identify regulatory elements in the genome that are important for cancer progression.
