Oncogenic viruses contribute to cancer through various mechanisms:
Integration into Host Genome: Some viruses, like HPV and HBV, integrate their genetic material into the host genome, causing mutations that lead to cancer. Chronic Inflammation: Persistent infection with viruses like HCV can cause chronic inflammation, which contributes to DNA damage and cancer. Immune System Suppression: EBV and KSHV can impair the immune system's ability to detect and destroy cancerous cells. Oncogene Activation: HTLV-1 can activate oncogenes that promote uncontrolled cell growth.
