How Does Allosteric Regulation Differ from Other Forms of Regulation?
Allosteric regulation is distinct from competitive inhibition and covalent modification. Competitive inhibitors compete with the substrate for the active site, while allosteric regulators bind to a separate site. Covalent modifications, such as phosphorylation, involve the addition or removal of a chemical group. Allosteric regulation can offer more fine-tuned control, as it often involves subtle conformational changes rather than complete blockage or activation.
